李林楠

linnanli@shutcm.edu.cn

致力于发展质谱、色谱与样品前处理新技术，实现复杂天然药物体系的精准分析。

北京大学分析化学博士 · 四川大学化学学士

✉ 电子邮件 Google Scholar ORCID

研究方向

研究贯穿天然药物分析的完整链条——从活性成分的发现与表征，到分子作用机制的解析，再到产品质量与安全的保障。

分析技术创新

质谱 · 色谱 · 样品前处理

发展质谱、色谱与样品前处理新方法，用于复杂天然药物体系的精准分析。

活性成分发现

天然产物

中药中生物活性成分的发现与结构表征。

靶向分析与代谢组学

代谢组学 · 分子靶向

通过内源性分子靶向分析与代谢组学，揭示作用机制。

质量控制与安全性

绿色化学 · 质量控制

绿色化学策略，以及天然产物的质量控制与安全性评价。

所属平台与联系方式

所属平台

中药功效成分发掘与利用全国重点实验室

中药标准化教育部重点实验室

中药新资源与品质评价国家中医药管理局重点研究室

上海市复方中药重点实验室

联系方式

上海市浦东新区张江科学城蔡伦路1200号
上海中医药大学中医药标准化大楼 908 室（邮编 201203）
电话：+86-21-51322417
邮箱： linnanli@shutcm.edu.cn

代表性论文

J. Pharm. Anal.

Unraveling pyrrolizidine alkaloid-induced liver damage with an integrative spatial lipidomics framework

Yilin Chen, Jie Xu, Thomas Ka-Yam Lam, Yanqiao Xie, Jianing Wang, Aizhen Xiong, Zhengtao Wang, Zongwei Cai, Linnan Li^*, and Li Yang^*

Journal of Pharmaceutical Analysis, 2026

DOI Bib

@article{chen2025jpa,
  title = {Unraveling pyrrolizidine alkaloid-induced liver damage with an integrative spatial lipidomics framework},
  author = {Chen, Yilin and Xu, Jie and Lam, Thomas Ka-Yam and Xie, Yanqiao and Wang, Jianing and Xiong, Aizhen and Wang, Zhengtao and Cai, Zongwei and Li, Linnan and Yang, Li},
  journal = {Journal of Pharmaceutical Analysis},
  volume = {16},
  number = {1},
  pages = {101340},
  year = {2026},
  doi = {10.1016/j.jpha.2025.101340},
}

J. Adv. Res.

Rare ginsenosides: a unique perspective of ginseng research

Wenxiang Fan, Linhong Fan, Ziying Wang, Yuqi Mei, Longchan Liu, Linnan Li, Li Yang^*, and Zhengtao Wang^*

Journal of Advanced Research, 2024

DOI Bib

@article{fan2024jar,
  title = {Rare ginsenosides: a unique perspective of ginseng research},
  author = {Fan, Wenxiang and Fan, Linhong and Wang, Ziying and Mei, Yuqi and Liu, Longchan and Li, Linnan and Yang, Li and Wang, Zhengtao},
  journal = {Journal of Advanced Research},
  volume = {66},
  pages = {303--328},
  year = {2024},
  doi = {10.1016/j.jare.2024.01.003},
}

Anal. Chem.

Ion mobility mass spectrometry for the separation and characterization of small molecules

Longchan Liu, Ziying Wang, Qian Zhang, Yuqi Mei, Linnan Li^*, Huwei Liu, Zhengtao Wang, and Li Yang^*

Analytical Chemistry, 2023

DOI Bib

@article{liu2023analchem,
  title = {Ion mobility mass spectrometry for the separation and characterization of small molecules},
  author = {Liu, Longchan and Wang, Ziying and Zhang, Qian and Mei, Yuqi and Li, Linnan and Liu, Huwei and Wang, Zhengtao and Yang, Li},
  journal = {Analytical Chemistry},
  volume = {95},
  number = {1},
  pages = {134--151},
  year = {2023},
  doi = {10.1021/acs.analchem.2c02866},
}

Mass Spectrom. Rev.

Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals

Yilin Chen#, Yanqiao Xie#, Linnan Li^*, Zhengtao Wang, and Li Yang^*

Mass Spectrometry Reviews, 2023

DOI Bib

@article{chen2023msr,
  title = {Advances in mass spectrometry imaging for toxicological analysis and safety evaluation of pharmaceuticals},
  author = {Chen#, Yilin and Xie#, Yanqiao and Li, Linnan and Wang, Zhengtao and Yang, Li},
  journal = {Mass Spectrometry Reviews},
  volume = {42},
  number = {5},
  pages = {2207--2233},
  year = {2023},
  doi = {10.1002/mas.21807},
}

Coord. Chem. Rev.

Recent advances in applications of metal–organic frameworks for sample preparation in pharmaceutical analysis

Linnan Li, Yilin Chen, Li Yang, Zhengtao Wang^*, and Huwei Liu^*

Coordination Chemistry Reviews, 2020

DOI Bib

@article{li2020ccr,
  title = {Recent advances in applications of metal–organic frameworks for sample preparation in pharmaceutical analysis},
  author = {Li, Linnan and Chen, Yilin and Yang, Li and Wang, Zhengtao and Liu, Huwei},
  journal = {Coordination Chemistry Reviews},
  volume = {411},
  pages = {213235},
  year = {2020},
  doi = {10.1016/j.ccr.2020.213235},
}